Local drivers have been told to expect more traffic in the area and to take care while driving as South32 increases stockpiles.
Up to five trucks will be travelling in and around Worsley Refinery over the next six months, transporting coal, hydrate and biomass.
According to a South32 spokesperson, the increased traffic will peak from mid-August to the end of September.
"We are replenishing and increasing coal stockpiles at Worsley Alumina over the next few months, from local suppliers, to provide flexibility in the event of any potential future supply distributions," she said.
"The refinery received deliveries by rail from both Griffin Coal and Premier Coal, however due to rail network constraints, they are also being made by road."
The trucks will be travelling on Coalfields and Forrest Highways and Throssell Street.
Industry Road Safety Alliance South West project manager Sarah Stanley said the foundation's members were working collaboratively with the mining giant to reduce road trauma during the increased traffic period.